Psoriasis is a chronic rash that affects 2-3% of the population. Although there is no cure, there is good treatment available. Did you know that some people with psoriasis can feel more tired than usual? Psoriasis associated fatigue is a well recognized issue that can interfere with many daily activities. This problem is most likely due to chronic inflammation found in the skin and blood. Some medications that are currently available to treat psoriasis may help to improve the feeling of fatigue or tiredness. Of course, as with many skin diseases, more research is needed to determine what is the best treatment for this condition.